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The approach is effective for First screening and classification of new psychoactive substances as a result of its ability to offer structural data by fragmentation patterns and comparison with spectral libraries
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NMR Investigation is very important for characterizing novel designer benzodiazepines and pinpointing prospective metabolites, which aids in creating in depth analytical profiles for forensic databases
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evitachem.comwikipedia.org. Patents for example US4155913A detail methodologies for getting ready thienotriazolodiazepine derivatives, indicating a systematic hard work to construct this core scaffold through that period
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Just one explained route starts with 2-chlorothiophene (B1346680) derivatives, proceeding through response with methylamine (B109427) less than reflux ailments, followed by purification actions which include column chromatography and recrystallization to accomplish large purity . The existence of the bromine atom at situation 2 in addition to a 2-fluorophenyl substituent at position four are essential structural attributes that distinguish this compound from related compounds like Brotizolam .
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